Experimental Ventilator-induced Lung Injury
نویسندگان
چکیده
منابع مشابه
Ventilator-induced lung injury.
From the Keenan Research Center, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, and the Department of Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto — both in Toronto (A.S.S.); and Dipartimento di Anestesia e Medicina degli Stati Critici, Ospedale S. Giovanni Battista Molinette, Università di Torino, Turin, Italy (V.M.R.). Address reprint requ...
متن کاملVentilator-induced lung injury.
Severe physical-trauma can lead to the development of acute respiratory distress syndrome (ARDS). Currently, the only known treatment for ARDS is mechanical ventilation. However, if mechanical ventilation is applied inappropriately further injury and malfunction of the lungs may occur, and thus, causing a ventilator induced lung injury (VILI). VILI has several manifestations including volutraum...
متن کاملVentilator-induced lung injury.
The clinical relevance of experimental ventilator-induced lung injury has recently received a resounding illustration by the Acute Respiratory Distress Syndrome Network trial that showed a 22% reduction of mortality in patients with acute respiratory disease syndrome when lung mechanical stress was lessened by tidal volume reduction during mechanical ventilation. This clinical confirmation of t...
متن کاملPre-treatment with dexamethasone attenuates experimental ventilator-induced lung injury.
OBJECTIVE To evaluate the effects that administering dexamethasone before the induction of ventilator-induced lung injury (VILI) has on the temporal evolution of that injury. METHODS Wistar rats were allocated to one of three groups: pre-VILI administration of dexamethasone (dexamethasone group); pre-VILI administration of saline (control group); or ventilation only (sham group). The VILI was...
متن کاملMechanisms of ventilator-induced lung injury.
OBJECTIVES To describe the physiologic mechanisms of ventilator-induced lung injury and to define the major ventilator and host-dependent risk factors that contribute to such injury. DATA SOURCE Basic science and clinical studies related to ventilator-induced barotrauma and lung pathophysiology. STUDY SELECTION Emphasis on controlled, experimental studies and clinical studies related to spe...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2009
ISSN: 0003-3022
DOI: 10.1097/aln.0b013e31819fcba9